The purpose of this study is to determine whether universal salt iodization (USI) meets the iodine requirements of pregnant women, lactating women and infants.
Because pregnant women, lactating women and infants are the groups most vulnerable to iodine deficiency and its irreversible consequences, programs should focus on these groups. But like other mass fortification strategies, it is uncertain whether USI can meet the increased dietary requirements of pregnant women, lactating women and infants. Objective of this study to test whether USI can meet the dietary requirements of iodine in women of reproductive age, pregnant women, lactating women and infants up to 2 years of age without causing excess iodine intake in school children and non-pregnant non-lactating women. The study hypothesis is that USI, when fortified at adequate levels and applied to all salt consumed, including both household salt and salt used for processed foods, provides adequate dietary iodine for all population groups, except for weaning infants; while not posing any risk of excessive iodine intakes in other age groups.
Study Type
OBSERVATIONAL
Enrollment
8,000
Shanxi Institute for Prevention and Treatment of Endemic Disease
Linfen, Shanxi, China
University of Zagreb
Zagreb, Croatia
University of Santo Tomas Hospital
Manila, Philippines
ETH Zurich
Zurich, Switzerland
Urinary iodine concentration (µg/L)
Participants will be assessed only once. However, for 30% of the study participants urinary iodine concentration will be assessed in spot samples collected on two different days, spread over an expected average of 5 days.
Time frame: 1 day
Thyroglobulin (µg/L)
Thyroglobulin will be measured in all population groups
Time frame: 1 day
Breast milk iodine concentration (µg/L)
Breast milk iodine concentration will be measured in lactating women.
Time frame: 1 day
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