Research of the Application of Triple Antibiotic Paste in Primary Teeth With Pericpical Periodontitis

N/AUnknownNCT02196740

Lin Jiacheng100 enrolled

Overview

The triple antibiotic paste is widely used in young permanent teeth and permanent teeth root canal therapy with excellent antiantimicrobial effect.We hypothesize that its application in the treatment of periapical periodontitis of deciduous teeth is superior to other drugs currently in use as creosote.

We design to collect a group of patients presenting primary teeth with periapical periodontitis in certain criterion. We will divide the patients into two groups randomly.One group will get treated with triple antibiotic paste while the other with creosote.We want to evaluate the short-term and long-term effects of the two groups to get a conclusion of the clinical value of triple antibiotic paste.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

100

Conditions

Periapical Diseases

Interventions

Metronidazole-Ciprofloxacin gatifloxacin-Clindamycin pasteDRUG

Pulp removal,Root canal irrigation and disinfection,

creosoteDRUG

Pulp removal,Root canal irrigation and disinfection

Eligibility

Sex: ALLMin age: 3 YearsMax age: 8 Years

Medical Language ↔ Plain English

Inclusion Criteria: * clinical diagnosis of periapical periodontitis * must be primary teeth * must be 3\~8 years old * the permanent tooth germ is complete and didnot be involved Exclusion Criteria: * blood disease * residual root that is advised to extract * serious periodontitis * allergy to the triple antibiotic paste

Locations (1)

Jicheng Lin

Guangzhou, Guangdong, China

Outcomes

Primary Outcomes

Evidence of lesion healing confirmed by cone beam computed tomography and X-rays

Time frame: 1 year

Data from ClinicalTrials.gov

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