This is a pilot study to determine if there are changes in heart function following completion of radiation therapy for breast cancer as measured by cardiac magnetic resonance imaging (cardiac MRI) scans. Additional purposes of this study are to assess cardiac side effects from radiation treatment, evaluate cardiac MRI changes by radiation technique, and compare quality of life questionnaires.
As part of this study, participants will have a cardiac MRI at baseline and a follow-up cardiac MRI within 1 year after completion of standard radiation therapy for left-sided breast cancer. The cardiac MRI scans will be evaluated to determine if there are changes in cardiac function within 1 year after radiation treatment. Patients will be asked to complete a questionnaire before and after treatment that asks about their health and any symptoms they may be having. Physical exams and any other standard of care service or treatment will be at the discretion of the treating physician.
Study Type
OBSERVATIONAL
Enrollment
24
Participants will have a cardiac MRI at baseline and within 1 year after completion of radiation therapy.
University of Florida Proton Therapy Institute
Jacksonville, Florida, United States
Proportion of participants with changes in cardiac function.
A change in cardiac function may include shifts from baseline measures of LV mass, strain, ejection fraction, and late gadolinium enhancement.
Time frame: 1 year after completion of radiation therapy
Proportion of patients with serious cardiac side effects.
Includes myocardial infarction, valve disorder, congestive heart failure, and angina.
Time frame: 1 year after completion of radiation therapy
Mean quality of life score.
Comparison of baseline and post treatment quality of life questionnaires completed by participants.
Time frame: 1 year after radiation treatment
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