Evaluation of the Timing of the Nebulization Related to the Physiotherapy Session

N/ACompletedNCT02201082

Cliniques universitaires Saint-Luc- Université Catholique de Louvain15 enrolled

Overview

The purpose of this study is to determine the optimal time for the nebulization depending on the respiratory physiotherapy session in cystic fibrosis patients.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Cystic Fibrosis

Interventions

Airway clearance techniquePROCEDURE

Amikacin nebulizationDRUG

Eligibility

Sex: ALLMin age: 16 YearsMax age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Stable cystic fibrosis patients older than 16 y.o. * Pseudomonas aeruginosa colonization * Hypersecretion Exclusion Criteria: * Kidney failure * No pregnancy

Locations (1)

Cliniques universitaires Saint-Luc

Brussels, Belgium

Outcomes

Primary Outcomes

Urinary excretion of amikacin

Pharmacokinetic study of the urinary excretion of amikacin after nebulization

Time frame: 24h after the nebulization

Secondary Outcomes

Amikacin concentration into the sputum

Time frame: At the end of the nebulization, an expected average of 20 minutes

Data from ClinicalTrials.gov

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