Magnetic Resonance Elastography in Infants

N/ATerminatedNCT02201472

Children's Hospital Medical Center, Cincinnati2 enrolled

Overview

MRI \& MRE in infants

The purpose of the present pilot study is to determine the feasibility of using MRI and MRE to evaluate the liver in infants with suspected liver disease.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Liver Disease

Interventions

MRI with MREDEVICE

Magnetic Resonance Imaging with Magnetic Resonance Elastography using the GE MR Touch device

Eligibility

Sex: ALLMax age: 6 Months

Medical Language ↔ Plain English

Inclusion Criteria: * Infants \< 6 months of age * Known liver disease based (liver enzymes, bilirubin, and/or GGT at least twice the upper limit of normal for age) * Parental/LAR permission obtained Exclusion Criteria: * Standard MRI exclusion criteria as set forth by the CCHMC Division of Radiology * Severe coagulopathy (INR \> 3 or platelets \<50,000)

Outcomes

Primary Outcomes

Feasibility of MRE to Provide Evaluable Images That Illustrate the Stiffness of Liver Parenchyma in an Infant Population

To determine the feasibility of MRE to provide evaluable images that illustrate the stiffness of liver parenchyma in an infant population.

Time frame: 12 months

Data from ClinicalTrials.gov

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