The Potential Biomark of Serious Psychosis:a Prospective,Case-controled Study

N/AUnknownNCT02202460

Central South University200 enrolled

Overview

Patients suffer from Serious Psychosis may have variation in immunological factors,BDNF and MRI.

Patients suffer from Schizophrenia and Mood Disorders may have variation in immunological factors(TNF-α,IL-2,IL-6,IL-10,etc),BDNF and Brain MRI.

Study Type

OBSERVATIONAL

Enrollment

200

Conditions

Other Immunological States or Disorders

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Diagnosis with Schizophrenia , Bipolar Disorder or Major Depression by DSM-5 Exclusion Criteria: * Unstable physical conditions

Locations (1)

Mental Health Institute of 2nd Xiangya Hospital,CSU

Changsha, Hunan, China

Outcomes

Primary Outcomes

Oxidative Stress-related Immunological Factors

Blood test will be conducted every 3 month to assess the concentration of oxidative stress-related immunological factors including TNFα,TGFβ， MCP-1，IL-1α，IL-2，IL-6，IL-10，IL-12.

Time frame: 18 month

Secondary Outcomes

BDNF

Collecting participants' blood every 3 month to assess the concentration of brain derived neurotrophic factor.

Time frame: 18 month

Central Contacts

Renrong Wu, PhD

CONTACT

+86 15874179855 wurenrong2013@163.com

Data from ClinicalTrials.gov

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