TITAN™ Reverse Shoulder System

Inclusion Criteria: * Subjects with grossly deficient rotator cuff with severe arthropathy or Subjects with failed joint replacement with grossly deficient rotator cuff * Subjects with a shoulder joint anatomically and structurally suited to receive the device * Subjects at least 21 years of age and skeletally mature at the time of surgery * Subject provided consent to participate in the clinical study (having signed the Informed Consent Form) Exclusion Criteria: * Subjects without a functional deltoid muscle * Subjects with active local or systemic infection * Subjects with inadequate bone stock in the proximal humerus or glenoid fossa for supporting the components * Subjects with poor bone quality such as osteoporosis where there could be considerable migration of the prosthesis and/or a chance of fracture of the humerus or glenoid * Subjects with muscular, neurologic, or vascular deficiencies that compromise the affected extremity * Subjects with known metal allergies * Subjects are known to be at risk for lost to follow-up, or failure to return for scheduled visits * Subjects who are prisoners * Female subject who are pregnant, nursing, or of childbearing potential while not practicing effective contraceptive methods