Phase 2a Study on Allogeneic Osteoblastic Cells Implantation in Lumbar Spinal Fusion

Inclusion Criteria: * Ability to provide a written, dated, and signed informed consent prior to any study related procedure, and to understand and comply with study requirements * Symptomatic degenerative disc disease of the lumbar spine requiring a single level lumbar fusion (L1-S1) * Unresponsive to non-operative treatment for at least 6 months Exclusion Criteria: * Lumbar disc disease requiring treatment at more than one level * Previous failed fusion at the involved lumbar level * Local active or latent infection at the involved lumbar level * Positive serology for hepatitis B, hepatitis C, HIV * Current or past medical disease that could interfere with the evaluation of the safety and efficacy, as judged by the investigator