Relationships Between Macular Pigment Optical Density and Lacquer Cracks in High Myopic Patients.

N/ACompletedNCT02205632

Poitiers University Hospital39 enrolled

Overview

Lutein ans zeaxanthin, carotenoids provided by dietary intake are mainly located in the macular area. Its absorption peak at 460 nm may reduce photic damages. The macular pigment density can be evaluated by its optical density. Reduced macular pigment level is a significant risk factor for age-macular degeneration. The nutritional intake can minimise the risk of age-macular degeneration.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Masking

NONE

Enrollment

Conditions

High Myopia

Interventions

MPS IIDEVICE

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age \>18 years-old * High axial myopia \< -6 dioptries * Presence or not of lacquer cracks in Bruch's membrane in one or both eyes * Patients with social security coverage Exclusion Criteria: * Age \<18 years-old * Amblyopia in the studied eye * Prior ocular surgery * Corneal disease or severe dry eye syndrome * Other retinal disease: diabetic retinopathy, age-related macular degeneration, macular hole, epiretinal membrane central * Extensive chorioretinal atrophy * Allergy to tropicamide * Pregnancy

Locations (1)

ophthalmology department, Poitiers University Hospital

Poitiers, Vienne, France

Outcomes

Primary Outcomes

Association between lacquer cracks related to high myopia and the macular pigment optical density

Time frame: 1 day

Secondary Outcomes

The macular pigment optical density among high myopic patients

Time frame: 1 day

Data from ClinicalTrials.gov

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