Combined Cataract Surgery and Planned Descemetorhexis

N/ACompletedNCT02206594

Medical College of Wisconsin2 enrolled

Overview

A pilot study designed to assess the feasibility of planned descemetorhexis for the treatment of Fuchs' corneal dystrophy.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Fuchs' Corneal Dystrophy Cataract

Interventions

DescemetorhexisPROCEDURE

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

General Inclusion Criteria: * Patient \>18 years old * Willing and able to provide informed consent Ocular Inclusion Criteria (all ocular inclusion criteria apply only to the study eye): * Fuchs' corneal dystrophy diagnosed * Cataract present * Best corrected visual acuity ≤ 20/40 * Candidate for current endothelial transplant procedure (DSAEK, DMEK) General Exclusion Criteria: * \<18 years old * Medically unstable patient * Monocular patient * Unwilling or unable to provide informed consent Ocular Exclusion Criteria (all ocular exclusion criteria apply only to the study eye): * Corneal dystrophy other than Fuchs' * Central corneal scar or central opacity not related to Fuchs' * Severe nonproliferative diabetic retinopathy or proliferative diabetic retinopathy * History of prior vitreoretinal surgery * Advanced or unstable glaucoma * Known steroid responders with glaucoma

Locations (1)

The Medical College of Wisconsin

Milwaukee, Wisconsin, United States

Outcomes

Primary Outcomes

Corneal clarity as assessed by slit lamp photography

Time frame: Assessed up to 1 year following descemetorhexis

Secondary Outcomes

Resolution of edema as assessed by slit lamp photography

Time frame: Assessed up to 1 year following descemetorhexis

Data from ClinicalTrials.gov

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