Postural Changes in Lung Volumes in Obesity

N/ACompletedNCT02207192

Association pour la Formation du Personnel à la Medecine d'Urgence12 enrolled

Overview

Postural changes are known to affect normal lung volumes. A reduction in sitting to supine functional residual capacity (FRC) is well-described in non-obese subjects adopting a supine position. However, postural changes in lung volumes in the obese require further exploration. We aimed to longitudinally address the effects of weight loss on postural changes in lung volumes and pulmonary function, in obesity. We tested the hypothesis that supine reduction in FRC would be absent in morbid obesity and recovered upon weight loss.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Obesity

Interventions

Postural change in lung volumes: sitting to SupineOTHER

Pulmonary function and arterial blood gases were assessed both prior to and after weight loss as part of pre-operative and 12-month follow-up evaluations. Pulmonary function tests were performed both in the sitting and then in the supine position.

Eligibility

Sex: ALLMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * subjects scheduled for bariatric surgery (BMI over or equal to 40 kg/m2) Exclusion Criteria: * Subjects with respiratory and cardiac history (asthma, COPD, heart failure) were excluded.

Locations (1)

Montpellier University hospital

Montpellier, France

Outcomes

Primary Outcomes

functional residual capacity

Time frame: baseline and one year after bariatric surgery

Secondary Outcomes

lung volumes and flows

Time frame: at baseline and after bariatric surgery

Data from ClinicalTrials.gov

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