Comparison of Bacteriostatic Saline to Buffered Lidocaine for Ultrasound Guided Hip Joint Injection Local Anesthesia

Phase 4CompletedNCT02209272

Mayo Clinic68 enrolled

Overview

The purpose of this study is to compare infiltration pain and anesthetic efficacy between lidocaine and Bacteriostatic saline (BS) for ultrasound (US) guided intraarticular hip injections.

Local anesthesia is commonly used to reduce pain during joint injections, particularly for deep joints like the hip. Lidocaine is the most commonly used local anesthetic in most medical practices. It is well known that lidocaine infiltration itself is painful. Many strategies have been studied to minimize pain associated with lidocaine administration, including buffering, warming, and slowing infiltration rate. BS is an alternative local anesthetic that has been shown to be less painful when injected into subcutaneous tissues compared with lidocaine. However, BS use has not been widely implemented for local anesthesia, and it has not been studied in the context of joint injections.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Hip Pain

Interventions

bacteriostatic salineDRUG

buffered lidocaineDRUG

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 YearsHealthy volunteers:

Medical Language ↔ Plain English

INCLUSION CRITERIA: * age 18-75 years * referred for US-guided intraarticular hip injections in the Mayo Clinic Sports Medicine Center, Physical Medicine \& Rehabilitation Clinic, or Musculoskeletal Clinic EXCLUSION CRITERIA: * chronic opioid use * opioid use on day of procedure * history of fibromyalgia or other diffuse chronic pain syndrome * pain behavior during the clinical encounter as judged by the injectionist * anesthetic administration time outside the designated 5-15 second time frame

Locations (1)

Mayo Clinic in Rochester

Rochester, Minnesota, United States

Outcomes

Primary Outcomes

VAS for Pain Score During Local Anesthesia Infiltration

The Visual Analog Scale (VAS) for Pain is a validated tool used to measure pain. A 100mm horizontal line anchored by "no pain" (score of 0) and "pain as bad as it could be" (score of 100).

Time frame: baseline to 5-10 minutes later -- immediately after local anesthetic injection administration

Secondary Outcomes

VAS for Pain Score During Subsequent Hip Joint Injection (Local Anesthetic Efficacy)

The Visual Analog Scale (VAS) for Pain is a validated tool used to measure pain. A 100mm horizontal line anchored by "no pain" (score of 0) and "pain as bad as it could be" (score of 100).

Time frame: baseline to 5-10 minutes later -- immediately after hip joint injection

Anesthetic Infiltration Duration

Anesthetic infiltration duration will be measured using a timer on the ultrasound machine, with goal administration between 20-40 seconds.

Time frame: baseline

Data from ClinicalTrials.gov

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