It has been shown that patients complaining of gas-related symptoms significantly improve on a diet low in fermentable residues. However, other studies suggest that some non-absorbable, fermentable meal products (prebiotics) that serve as substrate to colonic bacteria, produce beneficial effects to the host, including improvement of abdominal symptoms. The aim of the study is to compare the effects of a diet low in fermentable residues versus a diet suplemented with prebiotics on intestinal microbiota composition, microbiota activity (intestinal gas production) and digestive symptoms.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
40
Prebiotic versus low-FODMAPs diet
Vall d'Hebron Research Institute
Barcelona, Barcelona, Spain
Gut microbiota composition
Effect of treatment on the response of microbiota to 3-day challenge diet
Time frame: 28 days
Microbiota activity (intestinal gas production)
Intestinal gas evacuation on standardized diet
Time frame: 28 days
Digestive symptoms
Digestive sensations measured by scales
Time frame: 28 days
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