Insufficient intake of vitamin D is a public health problem, affecting about 40% of the Finnish population in the winter. Vitamin D has a wide range of health effects: in addition to its effect on bone, it is known to affect inflammatory response among other things. The sources of vitamin D are the synthesis in the skin as well as diet and dietary supplements. In Finland and in Northern Europe vitamin D is formed in the skin only from March to October. This alone is not sufficient to cover the need for year-round, because vitamin D storage is used in a few months. During the winter months the only sources of vitamin D are diet and vitamin preparations. Current vitamin D recommendations are usually based on studies in white population. However, there can be a difference in the need of vitamin D and in vitamin D metabolism between different population groups. More research evidence is needed from the northern countries. The aim of this study is to evaluate the vitamin D need in Somali immigrant population and in original Finnish population. The hypothesis is that the Somalis need more vitamin D to exceed the serum 25(OH)D concentration of 50 nmol/L than the original Finnish population.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
147
Department of Food and Environmental Sciences, University of Helsinki
Helsinki, Finland
Serum 25-hydroxyvitamin D (25(OH)D) concentrations
The effect of ethnicity on the serum 25(OH)D concentration response to vitamin D supplementation will be investigated.
Time frame: Change from baseline in serum 25(OH)D concentration at 3 and 6 months
Serum calcium concentration
Markers of calcium metabolism, which are affected by vitamin D, will be measured
Time frame: Change from baseline in serum calcium concentration at 3 and 6 months
Serum parathyroid hormone (PTH) concentration
Markers of calcium metabolism, which are affected by vitamin D, will be measured
Time frame: Change from baseline in serum PTH concentration at 3 and 6 months
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