Bordetella Pertussis Carriage in College-aged Students

University of Virginia150 enrolled

Overview

The objective in this observational cohort study of young adults sampled at three intervals during the academic year is to ascertain if there is carriage of B. pertussis in asymptomatic individuals. We hypothesize that in asymptomatic college students there is no carriage of B. pertussis detectable by polymerase chain reaction (PCR) assay.

Study Type

OBSERVATIONAL

Enrollment

150

Conditions

Carriage of Bordetella Pertussis

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Age 18 and above * Not immunosuppressed * Not HIV positive (not known to be/self-reported) * Able to tolerate swab procedures * Able to provide consent Exclusion Criteria: * No antimicrobial or immunosuppressive medications taken for chronic conditions

Locations (1)

University of Virginia Health System

Charlottesville, Virginia, United States

Outcomes

Primary Outcomes

Number of participants with B. pertussis by PCR in nasopharyngeal sample at first timepoint

Participants will be tested for B. pertussis by PCR at one visit in October 2014, 30 minutes.

Time frame: 30 minutes

Secondary Outcomes

Number of participants with B. pertussis by PCR in nasopharyngeal sample at second timepoint

Participants will be tested for B. pertussis by PCR at one visit in January 2015, 30 minutes.

Time frame: 30 minutes

Data from ClinicalTrials.gov

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