Effect of Multiple Subcisions on Rolling Acne Scars

N/AActive Not RecruitingNCT02216864

Northwestern University5 enrolled

Overview

The purpose of this study is to find out whether the use of multiple subcisions over several visits will improve the appearance of rolling acne scars compared to no treatment. This study was a pilot study designed to determine feasibility of this procedure.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Acne Scars

Interventions

Multiple SubcisionPROCEDURE

At the start of the procedure, a straight vitrectomy knife will be inserted subdermally and will be slowly advanced parallel to the dermis. Rapid advancement and retraction of the needle under the scarred area in a lancing motion will be performed to abrade the underside of the dermis followed by side to side sweeping motions attempting to break any fibrous attachments to the deeper tissues.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. Age 18 to 65 2. Have bilateral rolling acne scars on each side of their face 3. No active or ongoing acne. 4. The subjects are in good health 5. The subject has the willingness and the ability to understand and provide informed consent for the use of their tissue and communicate with the investigator. Exclusion Criteria: 1. Under 18 years of age 2. Pregnancy or Lactation 3. Subjects who are unable to understand the protocol or to give informed consent 4. Subjects with mental illness 5. Recent Accutane use in the past 6 months 6. Subjects prone to hypertrophic and keloidal scarring 7. Subjects reporting any blood diseases (HIV, Hepatitis, etc.) 8. Subjects reporting a history of Herpes (oral or genital)

Locations (1)

Northwestern University Feinberg School of Medicine, Department of Dermatology

Chicago, Illinois, United States

Outcomes

Primary Outcomes

Change in acne scarring compared to baseline after treatments

The change in acne scarring is measured using a quantitative global scarring grading system to compare baseline to the treatment.

Time frame: Baseline and 36 weeks

Data from ClinicalTrials.gov

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