Colorectal Polyp Resection Adequacy

Rush University Medical Center288 enrolled

Overview

The purpose of this study is to determine the best way to ensure that polyps are completely removed by evaluating the borders of the removed polyp. If a polyp is found that meets the size requirements for the study, the investigators will take extra biopsies of the margin to determine if there is any abnormal tissue or cancer at these borders.

Study Type

OBSERVATIONAL

Enrollment

288

Conditions

Polyp Resection Adequacy

Eligibility

Sex: ALLMin age: 40 YearsMax age: 80 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Age 40-80 Exclusion Criteria: * Coagulopathy (international normalized ratio \>2) * Inflammatory bowel disease or other active colitides * Polyps of index colonoscopy that were felt not to be completely resected or pedunculated * Familial adenomatous polyposis or hereditary polyposis * Potential hereditary cancer syndrome (Lynch Syndrome)

Locations (1)

Rush University Medical Center

Chicago, Illinois, United States

Outcomes

Primary Outcomes

The incomplete resection rates in polyps from Group 1 (clear margins) versus Group 2 (positive margins).

Define the frequency of free margins versus margins that have dysplasia to the cautery site in snare polypectomy. A free margin is defined as uninvolved or normal mucosa extending to the cautery margin at the polypectomy stalk.

Time frame: Between 3-6 months

Data from ClinicalTrials.gov

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