Virtual Chromoendoscopy for Distal Polyps

University of Erlangen-Nürnberg Medical School230 enrolled

Overview

To assess the accuracy of predicting histology with virtual chromoendoscopy for distal colorectal polyps according to the ASGE PIVI statement.

Study Type

OBSERVATIONAL

Enrollment

230

Conditions

Colorectal Polyps

Interventions

Prediction of histologyOTHER

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Written informed consent * Screening or surveillance colonoscopy Exclusion Criteria: * history of inflammatory bowel disease * poor bowel preparation * colectomy * anticoagulation * polyposis syndrome

Locations (1)

University Hospital Erlangen

Erlangen, Germany

Outcomes

Primary Outcomes

Effectivity of virtual chromoendoscopy

Upon visualization of a polyp in white-light, the location and size (as compared to open biopsy forceps or snare) are noted. Afterwards, virtual chromoendoscopy is used to visualize and enhance the mucosal vascular pattern and the mucosal surface pattern morphology of the polyp. The endoscopist makes a real time assessment of each polyp according to size, shape, Paris classification and surface characteristics including pit pattern and mucosal vascular pattern morphology, colour, and type of depression. Further, the endoscopist is assigning a level of confidence (high or low) to each real time prediction. Afterwards, all polyps are resected using standard techniques and processed for pathological evaluation. Each polyp is assessed by an experienced GI pathologist blinded to the real time prediction of polyp histology. Finally, real time and histological results are compared.

Time frame: 3 years

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.