The trial objectives were to investigate the tolerability and pharmacokinetics of 80 mg telmisartan and 2, 4 or 6 mg lacidipine administered concurrently.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
27
Cmax (Maximum measured concentration of the analyte in plasma)
Time frame: up to 72 hours after drug administration
Number of subjects with adverse events
Time frame: up to 72 hours after drug administration
AUC (Area under the concentration-time curve of the analyte in plasma)
Time frame: up to 72 hours after drug administration
tmax (Time from dosing to the maximum concentration of the analyte in plasma)
Time frame: up to 72 hours after drug administration
CL/F (Apparent clearance of the analyte in plasma following extravascular administration)
Time frame: up to 72 hours after drug administration
Vz/F (Apparent volume of distribution of the analyte during the terminal phase)
Time frame: up to 72 hours after drug administration
MRT (Mean residence time of the analyte in the body)
Time frame: up to 72 hours after drug administration
t½ (Terminal half-life of the analyte in plasma)
Time frame: up to 72 hours after drug administration
Number of subjects with abnormal changes in laboratory parameters
Time frame: up to 72 hours after drug administration
Number of subjects with clinically significant changes in vital signs
Time frame: up to 72 hours after drug administration
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.