Supplementation with DHA during pregnancy will increase gestational length and improve cognitive development.
This was a trial of supplementation with DHA during pregnancy to increase gestational length. Subjects were provided with 300 mg, 600 mg or placebo (olive oil) in a randomized design from week 24-26 of pregnancy until delivery. Gestational age, birth weight and birth length data were collected and infants growth at 2 and 4 months and cognitive development at 4 months and 1 year were measured.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Masking
QUADRUPLE
Enrollment
871
Pregnant women were given 600 mg DHA in the last trimester of pregnancy
Pregnant women were given 300 mg DHA in the last trimester of pregnancy and through the first 3 months of breastfeeding
Pregnant women in the control group received placebo of either olive oil or high oleic acid sunflower oil during the study period
Denver Health Hospitals and Clinics
Denver, Colorado, United States
Colorado State University
Fort Collins, Colorado, United States
Gestational Length
Length of gestation as measured by Last menstrual period method and US
Time frame: 13 weeks
Cognitive Development
Bayley's Scales of Infant Development measured at 4 months of age
Time frame: 4 months
Cognitive Development
Bayley's Scales of Infant Development measured at 12 months of age
Time frame: 12 months
Infant birth length
self-explanatory
Time frame: 13 weeks
Infant Growth Velocity
Change in infant length and weight from 2 to 4 months of age
Time frame: 2 months to 4 months of age
Infant birth weight
self-explanatory
Time frame: 13 weeks
Infant head circumference at birth
self-explanatory
Time frame: 13 weeks
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