Exercise training, as part of cardiac rehabilitation, is effective in improving functional capacity and quality of life in patients with coronary artery disease. Other cardiovascular and non-cardiovascular benefits have been reported, namely in glucose metabolism, skeletal muscle function, oxidative stress, vascular function, pulmonary circulation, ischaemia-reperfusion lesion and ventricular remodelling. However, the benefit of exercise training on systolic and diastolic function is controversial especially after acute myocardial infarction where no longitudinal study has evaluated diastolic function using modern echocardiographic parameters. The hypothesis is that a structured program of exercise training can improve systolic and diastolic function in patients after myocardial infarction.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
200
Cardiology Department Gaia Hospital Center
Gaia, Portugal
Myocardial early diastolic velocity at mitral annulus by tissue Doppler (E' velocity)
Determined by echocardiography; results in cm/s
Time frame: 4 months
Ratio between early diastolic filling velocity from mitral inflow and myocardial early diastolic velocity at mitral annulus by tissue Doppler (E/E' ratio)
Determined by echocardiography; no unit (ratio)
Time frame: 4 months
Myocardial systolic velocity at mitral annulus by tissue Doppler (S' velocity)
Determined by echocardiography; results in cm/s
Time frame: 4 months
Left ventriclular ejection fraction
Determined by echocardiography; results in %
Time frame: 4 months
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