It is just an observation study. The investigates want to explore the signal changes of resting state functional Magnetic resonance Imaging (fMRI) after light treatment in jaundice infants. Signal changes contain blood oxygenation level dependent (BOLD) and arterial spin labeling (ASL).Indicator of BOLD is amplitude of low-frequency fluctuation（ALFF).Indicator of ASL is cerebral blood flow (CBF). The investigates assume that the children with jaundice after light therapy, ALFF and CBF will change. Focus on the globus pallidus and subthalamic nuclei. The two brain regions were proved to be abnormal in MRI T1, T2 structure signal in kernicterus. Doctors observe the status of infants aside.Using monitoring probe can see clearly.
resting state fMRI scan light therapy the second time resting state fMRI scan
Study Type
OBSERVATIONAL
Enrollment
20
clinical routine treatment according to the doctor's advice
Center for Cognition and Brain Disorders
Hangzhou, Zhejiang, China
RECRUITINGamplitude of low-frequency fluctuation change before and after light treatment
It is indicator of blood oxygenation level dependent.
Time frame: before and after light treatment
cerebral blood flow change before after light treatment
It is indicator of arterial spin labeling.
Time frame: before and after light treatment
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.