Study to Measure Relaxation From Different Types of Focused Breathing Exercises

Phase 1TerminatedNCT02226744

Vanderbilt University Medical Center24 enrolled

Overview

Mind-body practices, such as yoga, ta'i chi, mindfulness and biofeedback, commonly use slow breathing techniques to induce physiological and mental relaxation. Medical research suggests that slow breathing techniques induce physiological relaxation. This 6 week study will compare the effects of different types of breathing. The hypothesis is that different breathing techniques produce different physiological and mental changes.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Breathing Mind-body Practices Yoga Meditation

Interventions

Focused BreathingBEHAVIORAL

Eligibility

Sex: ALLMin age: 30 YearsMax age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Age 30 to 50 years * English speaking Exclusion Criteria: * Hypertension * Heart disease: history of coronary artery disease, myocardial infarction, significant valvular disease, or congestive heart failure * Diabetes * Renal Disease * Anxiety Disorder * Depression * Other psychiatric conditions including schizophrenia or bipolar disorder * Attention-deficit-disorder or Attention-deficit-hyperactivity disorder * Musculoskeletal condition limiting capacity to perform yoga such as chronic lower back pain, chronic neck pain * Asthma * Chronic Obstructive Lung Disease * Obstructive Sleep Apnea * Smoker * Currently taking blood pressure medications, oral diabetic medication or insulin * Current participation in a mind-body practice/program * Current cancer other than non-melanoma skin cancer * Regular swimmer * Plays wind or brass musical instruments

Locations (1)

Vanderbilt University Medical Center

Nashville, Tennessee, United States

Outcomes

Primary Outcomes

Magnitude of changes in heart rate response to upright position

Time frame: 10 minutes at baseline, 2 weeks and 6 weeks

Secondary Outcomes

Magnitude of changes in heart rate variability measured as ratio of low frequency to high frequency ratio components (Hz)

Time frame: Baseline, 2 weeks, and 6 weeks

Magnitude of changes in catecholamines in response to upright position

Time frame: 10 minutes at baseline, 2 weeks, and 6 weeks

Data from ClinicalTrials.gov

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