Fecal Microbiota Transplantation (FMT) in the Management of Active Ulcerative Colitis

Inclusion Criteria: 1. Age \> 18 and \< 65 years 2. Diagnosis of UC for \> 3 months but \< 5 years prior to screening as determined by the investigators 3. Those with mild to moderate UC 4. Those who have failed maintenance therapy with stable doses of 5-ASA, azathioprine or 6 mercaptopurine (6-MP) for \> 3 months 5. Where applicable, those who are taking the following medications must be at a stable dose defined as: i) 5-ASA must be at a stable dose for 2 weeks ii) Prednisone up to 20 mg/d must be at a stable dose for 2 weeks iii) Budesonide up to 6 mg/d must be at a stable dose for 2 weeks iv) Azathioprine or 6-MP must be at a stable dose for \> 8 weeks 6. ability to provide informed consent 7. evidence of active inflammation Exclusion Criteria: 1. Those whose disease is limited to the rectum (ie. proctitis) 2. Those with colectomy or diverting ileostomy 3. Those who are pregnancy or plan to be pregnant during the trial 4. Those who are breastfeeding or plan to breast feed during the trial 5. Those who are on or have previously failed a biological agent 6. Those with an active infection requiring antibiotic therapy 7. Those with positive stool cultures for known pathogens such as E coli, Salmonella, Shigella, Yersinia, Campylobacter, and Clostridium difficile toxin within 2 weeks of enrollment 8. Those with positive CMV on colonic tissue biopsy within 2 weeks of screening 9. Those with allergy to ciprofloxacin and metronidazole 10. Those with colonic mucosal dysplasia