The purpose of this study is to evaluate the safety and efficacy of Canagliflozin (TA-7284) in combination with GLP-1 analogue in patients with type 2 Diabetes for 52 weeks.
This is an open-label study to evaluate the long-term safety and efficacy of Canagliflozin (TA-7284) in Japanese patients with type 2 diabetes mellitus, who are receiving treatment with GLP-1 analogue on diet and exercise and have inadequate glycemic control. The patients will receive TA-7284 100mg orally for 52 weeks.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
71
The patients will receive Canagliflozin orally for 52 weeks
Reserch site
Chūbu, Japan
Reserch site
Hokkaido, Japan
Reserch site
Kanto, Japan
Reserch site
Kinki, Japan
Safety and Tolerability Assessed by Adverse Events (Number of Participants Experiencing With Adverse Events)
Time frame: 52 Weeks
Change in Percentage of HbA1c
Time frame: Baseline, 52 Weeks
Change in Fasting Plasma Glucose
Time frame: Baseline, 52 Weeks
Percentage Change in Body Weight
Time frame: Baseline, 52 Weeks
Change in Blood Pressure
Time frame: Baseline, 52 Weeks
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