Effect of Chronic Intranasal Oxytocin Administration on Sexual Function in Pre- and Postmenopausal Women

Inclusion Criteria: * Willingness to attempt sexual intercourse and/ or masturbation at least two times per week * Ongoing relationship for at least 3 months * Female subjects aging 40 years and more, Male subjects must be older than 18 * The participation in this study should be of free choice to male partners * Willingness to perform a pregnancy test every month (for pre-menopausal subjects) * Willingness to use contraception during the study period (for pre-menopausal subjects) * Normal findings in the urogenital tract unless the investigator considers an abnormality to be clinically irrelevant * Normal laboratory values unless the investigator considers an abnormality to be clinically irrelevant * Normal findings in the medical history and physical examination unless the investigator considers an abnormality to be clinically irrelevant Exclusion Criteria: * Primary sexual dysfunction * sexual abuse * severe psychiatric diseases * untreated conditions and medication intake with associated reduction of sexual function. * In male partners: any severe andrological or related medical problem.