Effects of Aloe Vera Toothpaste on Periodontal Parameters

Islamic Azad University, Sanandaj20 enrolled

Overview

This study aimed to assess the effects of Aloe Vera toothpaste on dental plaque and gingivitis. The single-blind cross-over clinical trial was conducted on 20 dental students (10 males and 10 females with a mean age of 24.5±4 yrs.) with gingivitis. Students were randomly divided into 2 groups. The first group used Aloe Vera toothpaste for 30 days. A 2-week wash-out period was allowed and then subjects used fluoride toothpaste for the next 30 days . This order was reversed in group 2.

Toothpastes are used with tooth brushing to better control microbial plaque. Herbal toothpastes have recently gained attention. This study aimed to assess the effects of Aloe Vera toothpaste on dental plaque and gingivitis. This single-blind cross-over clinical trial was conducted on 20 dental students (10 males and 10 females with a mean age of 24.5±4 yrs.) with gingivitis. Students were randomly divided into 2 groups. The first group used Aloe Vera toothpaste for 30 days and then their plaque index (PI) and gingival index (GI) were recorded. A 2-week wash-out period was allowed and then subjects used fluoride toothpaste for the next 30 days and underwent PI and GI assessment again. This order was reversed in group 2. Wilcoxon-Sign Rank and two way Repeated Measure ANOVA tests were applied for statistical analysis.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

Conditions

Gingivitis

Interventions

Foramen Herbal Aloe toothpasteOTHER

use of aloe-vera toothpaste for 30 days in the test group.

fluoride toothpasteOTHER

use of signal toothpaste once a day for 30 days in the control group.

Eligibility

Sex: ALLMin age: 20 YearsMax age: 24 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Subjects were selected among dental students with at least 20 natural teeth without systemic disease * No periodontal treatment at least 6 months to the study * No use of systemic antibiotic and anti-inflammatory drugs within the last 3 months, nonsmokers, no pregnancy or lactating women * Subjects with PD≤3mm, (clinical attachment level)CAL\<1mm, PI≥2 and gingival bleeding in more than 30% of the tested areas were enrolled with the diagnosis of plaque-related gingivitis. Exclusion Criteria: * Subjects with orthodontic appliances ,multiple bridges, partial denture, multiple caries were excluded from the study

Locations (1)

Tehran Dental Branch, Islamic azad University

Tehran, Tehran Province, Iran

Outcomes

Primary Outcomes

measuring gingival index

to compare the efficacy of the aloe-vera toothpaste with a known conventional toothpaste, the gingival index was recorded at baseline and after 30 days of consumption and compared with the two understudy toothpastes.

Time frame: 1-2days

Secondary Outcomes

measuring gingival index

Time frame: 1-2 days

measuring plaque index

to compare the efficacy of the aloe-vera toothpaste with a known conventional toothpaste, the plaque index was recorded at baseline and after 30 days of consumption and compared with the two understudy toothpastes.

Time frame: 1-2 days

Data from ClinicalTrials.gov

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