The purpose of this study is to observe the effect of lack or excess of folic acid in first, second and third trimester on child birth weight, fat content and the secretion of metabolism related hormone, and clinical follow-up their offspring obesity.
Study Type
OBSERVATIONAL
Enrollment
20,000
Nanjing Maternal and Child Health Care Hospital Affiliated to Nanjing Medical University
Nanjing, Jiangsu, China
The level of folate acid of pregnancy women at first trimester
Time frame: 12 weeks of pregnancy
The level of folate acid of pregnancy women at second trimester
Time frame: 20-24 weeks of pregnancy
The level of folate acid of pregnancy women at third trimester
Time frame: 28-40 weeks of pregnancy
The birth weight, fat content and metabolism related hormone secretion of their offspring
Time frame: At birth
The weight, fat content and metabolism related hormone secretion of their offspring at one year old
Time frame: One years old
The weight, fat content and metabolism related hormone secretion of their offspring at 3 years old
Time frame: 3 years old
The weight, fat content and metabolism related hormone secretion of their offspring at 5-7 years old
Time frame: 5-7 years old
The weight, fat content and the secretion of metabolism related hormone of offspring at 18 years old
Time frame: 18 years old
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