The purpose of this registry is to assess clinical outcomes, and different factors that may affect these clinical outcomes such as systems of care, associated with the use of Covidien market-released neurothrombectomy devices intended to restore blood flow in patients experiencing acute ischemic stroke due to large intracranial vessel occlusion.
This is a prospective, multi-center, non-randomized, observational registry of acute ischemic stroke patients that have or will undergo treatment with the use of a Covidien market-released neurothrombectomy device (as the initial device used to remove the thrombus) within 8 hours of stroke symptom onset, at the discretion of the investigator and independent of participation in this registry. This registry may enroll up to 1000 patients.
Study Type
OBSERVATIONAL
Enrollment
984
Number of Participants Assessed for Revascularization With mTICI Grades 2b-3
Assess revascularization using modified Thrombolysis in Cerebral Infarction (mTICI) score at the end of the procedure. This scale determines the response of therapy for ischemic stroke based on angiographic appearances of the treated occluded vessel and the distal branches. Classification: grade 0: no perfusion grade 1: antegrade reperfusion past the initial occlusion, but limited distal branch filling with little or slow distal reperfusion grade 2a: antegrade reperfusion of less than half of the occluded target artery previously ischemic territory grade 2b: antegrade reperfusion of more than half of the previously occluded target artery ischemic territory grade 3: complete antegrade reperfusion of the previously occluded target artery ischemic territory, with absence of visualized occlusion in all distal branches (higher values represent better outcomes)
Time frame: Day 0-At the completion of the thrombectomy procedure
Incidence of Neurological Events of Interest
Evaluate events causing neurological deterioration (defined as ≥ 4 worsening points from baseline on the NIHSS scale)
Time frame: up to 90 days post index procedure
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Banner University Medical Center
Phoenix, Arizona, United States
University of Arizona Medical Center
Tucson, Arizona, United States
University of California Irvine
Irvine, California, United States
University of California Los Angeles
Los Angeles, California, United States
Mercy San Juan Medical Center/ Mercy General
Sacramento, California, United States
California Pacific Medical Center
San Francisco, California, United States
Los Robles Medical Center
Thousand Oaks, California, United States
Advanced Neuroscience Network/Tenet South Florida
Delray Beach, Florida, United States
South Broward Hospital
Hollywood, Florida, United States
Baptist Medical Center - Jacksonville
Jacksonville, Florida, United States
...and 45 more locations