Venous Occlusion and Limb Swelling

Imperial College London1 enrolled

Overview

Problems affecting the veins in the legs can cause discomfort and swelling. We want to see how artificially and reversibly blocking the leg veins affects swelling in the lower limb.

Study Type

INTERVENTIONAL

Allocation

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Venous Occlusion

Interventions

Venous occlusion (leg tourniquet, made in-house)DEVICE

Leg occlusion applied via a blood pressure cuff. Venous occlusion checked using duplex ultrasound

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Over 18 years old, able to consent Exclusion Criteria: * History of cardiovascular/renal disease

Locations (1)

Charing Cross Hospital

London, United Kingdom

Outcomes

Primary Outcomes

Leg Swelling

Perometer measured leg volume from footplate to middle of knee joint (in standing position; ml)

Time frame: 30 minutes

Secondary Outcomes

Venous Diameter

Great saphenous vein diameter at the knee, taken with duplex ultrasound (cm)

Time frame: 30 minutes

Data from ClinicalTrials.gov

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