Coronally Advanced Flap With or Without Porcine Collagen Matrix for Root Coverage

Enilson Antonio Sallum40 enrolled

Overview

The purpose of this study is to compare the clinical outcomes after coronally advanced flap technique (CAF) associated or not to a porcine collagen matrix graft (CM) in the treatment of single gingival recessions. For this blinded randomized controlled clinical trial, 40 patients with Miller Class I or II gingival recession ≥ 2 mm in canines or premolars will selected and randomly assigned to receive either CAF or CAF+CM. The clinical parameters evaluated will be probing depth, clinical attachment level, gingival recession height, height and thickness of keratinized tissue. Clinical measurements will be taken at baseline and 45 days, 2, 3 and 6 months after surgery.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Gingival Recession

Interventions

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age ≥ 18 years. * Presence of at least one Class I or II Miller gingival recession ≥ 2 mm in maxillary canines or premolars with identifiable cementum-enamel junction (CEJ) and without deep non-carious cervical lesions (\< 0.5 mm): A + (Pini-Prato et al. 2010). * Aesthetic complaint and/or presence of dentin hypersensitivity to air stimulus. * Full-mouth visible plaque index ≤ 20% (Ainamo \& Bay 1975). * Full-mouth sulcus bleeding index ≤ 20% (Mühlemann \& Son 1971). Exclusion Criteria: * Smoking. * Pregnancy. * Presence of systemic disorders (diabetes, hypertension, heart disease or any other condition that could contraindicate periodontal surgery). * Use of medications (immunosuppressants, phenytoin or anything else that might affect mucosal healing and repair). * Previous periodontal surgery in the area.

Outcomes

Primary Outcomes

Recession Reduction

Measured as a difference between gingival margin between gingival recession depth at baseline and gingival recession at 6 months follow-up.

Time frame: 6 months

Secondary Outcomes

Complete root coverage

Assessed as percentage of sites with complete root coverage