Respiratory Muscles and Inspiratory Muscle Training

University of British Columbia25 enrolled

Overview

The effects of inspiratory muscle training (IMT) remain controversial. Many studies have examined the effect IMT has on exercise performance, but any changes to the body that come from IMT have yet to be looked at. This study will look at how someone breathes can change after IMT. Understanding how IMT changes the body can help us use IMT in different treatments.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

SINGLE

Enrollment

Conditions

Respiratory Muscles Breathing Exercises

Interventions

Inspiratory Muscle TrainingOTHER

6-weeks of inspiratory muscle training

Sham Inspiratory Muscle TrainingOTHER

A sham training procedure that is meant to elicit no physiologic changes

Eligibility

Sex: MALEMin age: 19 YearsMax age: 39 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Recreationally active, 'Moderate' or 'High' category on International Physical Activity Questionnaire Short form questionnaire * Able to read and understand English * Pulmonary function within normal limits Exclusion Criteria: * History of or currently smoking * History or current symptoms of cardiopulmonary disease (including asthma and exercise induced asthma) * Currently participating and training in a sport at a provincial, national, or international level * Ulcer or tumor in the esophagus, a nasal septum deviation, or recent nasopharyngeal surgery * Allergies to latex or local anesthetic * Contraindications to exercise testing

Locations (1)

Centre for Heart Lung Innovation

Vancouver, British Columbia, Canada

Outcomes

Primary Outcomes

Diaphragm Electromyography

Using a multipair esophageal electrode catheter we will determine any changes to the electric activity of the diaphragm. Diaphragm electromyography (EMG) has been expressed as %max. This unit is determined as the ratio of average EMG value (uV) divided by the maximal EMG activity (uV) generated during a maximal respiratory maneuver (inspiratory capacity during exercise).

Time frame: Post Intervention - ie. immediately after 5 weeks of inspiratory muscle training

Secondary Outcomes

Accessory Respiratory Muscle Activation

Using surface electromyography to determine the activation patterns of accessory respiratory muscles (scalene and sternocleidomastoid). Data are expressed as %max. This value is determined by taking the average electromyography (EMG) activity divided by the maximal EMG activity generated during a maximal inspiratory maneuver (inspiratory capacity during exercise).

Time frame: Post-intervention - ie. immediately after 5 weeks of inspiratory muscle training

Data from ClinicalTrials.gov

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