Stem Cell Therapy in Incurable Neurological Disorders

Neurogen Brain and Spine Institute

Overview

The purpose of the study was to analyze the benefit of autologous mononuclear cell therapy in incurable neurological disorders.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Conditions

Neurological; Disorder, Nervous System

Interventions

Stem CellBIOLOGICAL

Intrathecal autologous bone marrow mononuclear cell transplantation

Eligibility

Sex: ALLMin age: 6 MonthsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * diagnosed cases of incurable neurological disorders * age above 6 months Exclusion Criteria: * presence of acute infections such as Human immunodeficiency virus/Hepatitis B Virus/Hepatitis C Virus * malignancies * bleeding tendencies * pneumonia * renal failure * severe liver dysfunction * severe anemia \[Hemoglobin \< 8\] * any bone marrow disorder * space occupying lesion in brain * other acute medical conditions such as respiratory infection and pyrexia * pregnancy * lactation

Locations (1)

Neurogen brain and spine institute

Navi Mumbai, Maharashtra, India

Outcomes

Primary Outcomes

Change in various clinical symptoms of neurological disorders

Change in various symptoms such as muscle strength, limb strength, ambulation, neck holding, bladder bowel management, spasticity, sensation, speech, etc depending on the disorder will be recorded at 1 year follow up. Percentage analysis of each symptom will be carried out to study the benefits of stem cell therapy on them.

Time frame: 1 year

Data from ClinicalTrials.gov

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