Comparison of Autogenous Periosteal Pedicle Graft and Collagen Membrane in Management of Periodontal Intrabony Defects

Inclusion Criteria: * Severe chronic periodontitis patients with at least two sites with pocket depth ≥ 6 mm and clinical attachment level ≥ 5 mm, with radiographic evidence of bone loss 2- or 3-wall intrabony defect depth ranging from 3 to 6 mm as detected in periapical radiographs * The facial surface of teeth adjacent to the interproximal defect should be free of extensive recession and marginal bone loss, with at least a 4 to 5 mm band of keratinized gingiva to allow for periosteal manipulation Exclusion Criteria: * Pregnant women * Subjects had \<22 permanent teeth * Having any given systemic disease * Taking any type of medication and/or antibiotic therapy during the 3 months before the study * Received periodontal treatment within the past 12 months * Current or former smokers