CKD-828 (80/5mg) Pharmacokinetic Study

Inclusion Criteria: * A healthy volunteer between 20 and 55 years old * More than 50kg and within 20% of ideal body weight * No any congenital or chronic diseases and medical symptom * Appropriate for the study from examination(laboratory test, ECG etc.) within 4weeks prior to the first IP administration * Signed the informed consent form prior to the study participation. Exclusion Criteria: * History of relevant hypersensitivity against drug * Clinical significant disease or medical history (ex. hepato/cholangio, cardio, endo, hemato, onco, CNS etc.) * Active liver disease or abnormal laboratory result (AST or ALT or Total bilirubin \> 1.5\*ULN) * SBP \<90mmHg or SBP \>150mmHg * DBP \<50mmHg or DBP \>100mmHg * Creatinine clearance \<80mL/min * A Disease(ex.inflammatory intestinal disease, gastric or duodenal ulcer ,hepatic disease history , gastro-intestinal surgery except for appendectomy)that may influence on the absorption, distribution, metabolism and excretion of the drug * The evidence of severe attack or acute disease or surgical intervention within 28 days prior to the first IP administration. * A drug abuse or a heavy caffeine consumer (more than 5 cups per a day) or regular alcohol consumer(more than 21 units/week) or a heavy smoker(more than 10 cigarettes per a day) * Taking ETC medicine or oriental medicine within 14days or Taking OTC medicine within 7days prior to the first IP administration * Abnormal diet(Especially, grapefruit juice within 7 days prior to the first IP administration) that may influence on the absorption, distribution, metabolism and excretion of the drug