Metformin Extended Release Versus Metformin Immediate Release in Subjects With Type 2 Diabetes

Inclusion criteria: * Diagnosis of Type 2 diabetes mellitus before the screening visit based on the World Health Organization (WHO) diagnostic and classification criteria * HbA1c value of 7.0-10.0%, inclusive * Age ranging from 18 to 79 years, inclusive * Treatment-naive for oral antidiabetic agents (that is, had not received antidiabetic medication previously, or had received antidiabetic medication for at least 14 days and not within 1 month of enrolment) * Male, or non-pregnant, non-breastfeeding females * Body mass index (BMI) greater than or equal to (\>=) 18.5 and less than (\<) 35 kilogram per square meter (kg/m\^2) * In the opinion of the investigator, subjects are well-motivated, capable and willing to continue the study treatment as required during the whole study period, maintain a study dietary, as required for this protocol, attend scheduled visits and be willing to receive phone calls between visits, avoid pregnancy by using an adequate method of contraception throughout the duration of the study for the female subjects of child bearing potential (and if appropriate male subjects with female partners of childbearing potential) * Written informed consent given before any trial-related activities are carried out Exclusion criteria: * Type 1 diabetes * Previous treatment with insulin or other antidiabetics (including Chinese traditional medicine) for more than 14 days continuously or within 1 month of enrolment * Any of the protocol-specified cardiovascular conditions within 3 months prior to the screening visit * Impaired liver function as defined in the protocol * Serum creatinine values as specified in the protocol * Known proliferative retinopathy or maculopathy requiring acute treatment, or recurrent major hypoglycemia or hypoglycemic unawareness as judged by the investigator * Persistent uncontrolled hypertension * Severe chronic gastrointestinal disease * Previous history of 1 or more episodes of ketoacidosis or hyperosmolar state/coma * Currently receiving chronic (\>14 days) systemic glucocorticoid therapy (excluding topical, intraocular, inhaled or intranasal preparations) or have received such therapy within 4 weeks of the screening visit * Current use of beta-blockers, thiazide diuretic, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, nifedipine and isoniazid and cannot be replaced by any other treatment * Have any hematologic condition that may interfere with HbA1c measurement (for example, hemolytic anemia, sickle-cell disease) * Have any other condition (such as, known drug or alcohol abuse or a psychiatric disorder) that may prevent the subject from following and completing the protocol * Known hypersensitivity to Metformin Hydrochloride * Currently enrolled in, or discontinued within the last 30 days from, a clinical trial involving an investigational product or non-approved use of a drug or device, or concurrently enrolled in any other type of medical research judged not to be scientifically or medically compatible with this study * Any contraindications to Metformin according to local package insert