The aim of this pilot study is to evaluate the effects of one regular fasting day per week over a total period of 8 weeks compared to a normal-eating habits among healthy volunteers.
Participants in the intervention group receive an initial group training for fasting. Then all participants will observe one fixed fasting day per week (monday) over a total period of eight weeks. Participants in the control group receive an initial group training for healthy diet according to current German guidelines (DGE). Moreover, they will receive the same offer as in the intervention group at the end of the 8-week study period. Until then the control group participants follow a regular healthy diet.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
36
Immanuel Hospital Berlin
Berlin, State of Berlin, Germany
Insulin-like growth factor 1 and brain-derived neurotrophic factor
Measurement of changes after 8 weeks
Time frame: Baseline and after 8 weeks
Quality of life questionnaire: WHO-5
Questionnaire
Time frame: Baseline, 8 weeks, 6 month
Profile of mood states questionnaire: POMS
Questionnaire
Time frame: Baseline, 8 weeks, 6 month
Anxiety and depression questionnaire: HADS
Questionnaire
Time frame: Baseline, 8 weeks, 6 month
Flourishing questionnaire
Questionnaire
Time frame: Baseline, 8 weeks, 6 month
Visual analogue scales and Likert-scales
Questionnaire
Time frame: Baseline, 8 weeks, 6 month
Body Impedance Analysis (BIA)
Measurement of changes after 8 weeks
Time frame: Baseline, 8 weeks
Body weight and abdominal circumference
Measurement of changes after 8 weeks
Time frame: Baseline, 8 weeks
Systolic and diastolic bloodpressure
Measurement of changes after 8 weeks
Time frame: Baseline, 8 weeks
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Blood: total cholesterol, LDL, HDL, Triglycerides; Insulin, GOT,GPT, GGT, AP; HbA1c; PTT, INR
Changes after 8 weeks
Time frame: Baseline and 8 weeks