The prevalence of cervical neoplasia in Cambodia is not known. There are no screening programs in place. The investigators plan on introducing a screening program based on WHO criteria and utilizing visualization with acetic acid. Patients who are positive will be offered same-day cryotherapy if indicated or will be referred for biopsy, LEEP and hysterectomy as indicated. The planned patient pool for this study is 1000 women, half of whom will be HIV positive (and thus have a presumed higher incidence of cervical neoplasia).
Study Type
OBSERVATIONAL
Enrollment
1,000
These interventions and their outcomes are not part of this study. However, we will be offering at no charge appropriate treatment for neoplasia or cancer that is diagnosed.
Sihanouk Hospital, St. 134, Sangkat Vealvong, Khan 7 Makara
Phnom Pehn, Cambodia
Prevalence of cervical neoplasia in HIV positive women
500 HIV positive women will be screened for cervical neoplasia using direct visualization with acetic acid
Time frame: up to 12 months
Prevalence of cervical neoplasia in HIV negative women
500 HIV negative women will be screened for cervical neoplasia using direct visualization with acetic acid
Time frame: up to 12 months
Treatment of HIV positive women who screen as positive
Patients who screen positive will be offered same-day cryotherapy, further diagnostic work-up, and further therapeutic options such as LEEP and hysterectomy as clinically indicated.
Time frame: up to 12 months
Treatment of HIV negative women who screen as positive
Patients who screen positive will be offered same-day cryotherapy, further diagnostic work-up, and further therapeutic options such as LEEP and hysterectomy as clinically indicated.
Time frame: up to 12 months
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