Prediction of Pain After Total Knee Arthroplasty

Rigshospitalet, Denmark60 enrolled

Overview

Despite improvements in treatment, a significant part of patients have severe pain following knee arthroplasty. Preoperative identification of high-risk patients would allow for an intensive individualized analgesic treatment pre- and postoperatively and thus potentially in reduced pain acute and chronically.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Knee Osteoarthritis

Eligibility

Sex: ALLMin age: 50 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * primary unilateral TKA * caucasian * 50 - 80 years * osteoarthritis Exclusion Criteria: * deficient written or spoken danish * impairment from psychological og neurological disease * expected discharged to rehabilitation facility * anticoagulant therapy * allergies to analgesic treatment * hypertension (systolic \> 160 / diastolic \> 100) * ASA class ≥ 4

Locations (1)

Gentofte Hospital

Hellerup, Denmark

Outcomes

Primary Outcomes

Pain

Pain intensity on a NRS from 0 to 10 upon ambulation 24 hours following surgery

Time frame: 24 hours postoperatively

Secondary Outcomes

Pain

Pain intensity on a NRS (numeric rank scale) from 0 to 10 upon ambulation 48 hours following surgery

Time frame: 48 hours postoperatively

Pain

Daily diary reported pain intensity on a NRS (numeric rank scale) from 0 to 10 in average and when worse the first two weeks following knee arthroplasty.

Time frame: From day 1 to day 14 following surgery

Data from ClinicalTrials.gov

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