Irrisept Versus Standard of Care in the Prevention of Surgical Site Infections

Inclusion Criteria: 1. Is male or female, 18 years of age or older 2. Has provided written informed consent or has surrogate consent provided by a Legally Authorized Representative (LAR) 3. Has experienced abdominal trauma, blunt or penetrating, requiring open abdominal laparotomy with primary closure or 4. Has experienced acute surgical abdomen requiring open abdominal laparotomy with primary closure Exclusion Criteria: 1. Known allergy to Chlorhexidine Gluconate (CHG) 2. Estimated Abbreviated Injury Scale (AIS) score of six (6) at the time of surgery, for all trauma patients 3. American Society of Anesthesiologists Physical Status Classification (ASA) score of five (5) or greater (As ASA scoring is a subjective measure, if the PI finds the patient stable enough for study participation despite a score of 5, enrollment may continue.) 4. Female volunteers who are pregnant and/or breast feeding 5. Damage control laparotomy 6. Abdominal incision created prior to operating room (i.e. incision made in trauma bay to cross clamp the aorta) 7. Currently enrolled in an ongoing, interventional, randomized clinical trial