Postoperative Analgesia in Laminectomy

Diskapi Yildirim Beyazit Education and Research Hospital75 enrolled

Overview

Compare the analgesic effects of naproxen sodium codeine, paracetamol codeine and placebo on postoperative pain and tramadol (Contramal) consumption during the first 24 hour after a lumbar disk surgery.

Compare the analgesic effects of naproxen sodium codeine paracetamol codeine and placebo on postoperative pain intensity measured by the visual analogue scale, and evaluated tramadol consumption and related side effects.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Postoperative Pain Postoperative Laminectomy Pain

Interventions

550 mg naproxen sodium and 30mg codeineDRUG

Postoperative contramal consumption, pain intensity, side effects

300 mg paracetamol and 30 mg codeineDRUG

Postoperative contramal consumption, pain intensity, side effects

placebo tabletDRUG

Postoperative contramal consumption, pain intensity, side effects

Eligibility

Sex: ALLMin age: 16 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * American Society of Anesthesiologists (ASA) 1 or 2 status patients scheduled for an elective lumbar disc surgery Exclusion Criteria: * were known allergies to any of the drugs used in this study * peptic ulcer disease * hepatic and renal dysfunction, * emergency surgery * inability to provide informed consent

Outcomes

Primary Outcomes

Contramal consumption

To assess contramal consumption

Time frame: Postoperative 24 hour

Secondary Outcomes

Side effects

nausea and vomiting

Time frame: postoperative 24 hour

Pain intensity

To assess postoperative pain intensity by visual analog scale

Time frame: postoperative 24 hour

Central Contacts

Reyhan Polat, MD

CONTACT

+905326734310 reyhanp9@gmail.com

Data from ClinicalTrials.gov

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