HIFU in Patients With Non-malignant Thyroid Nodules

Inclusion Criteria: * Male or female patient 18 years or older. * Patient presenting with at least one thyroid nodule with no signs of malignancy: 1. Non suspect clinically and at ultrasonography imaging 2. Benign cytological diagnosis at fine-needle aspiration biopsy (FNAB) from the last 6 months 3. Normal serum calcitonin 4. No history of neck irradiation * Normal thyroid-stimulating hormone (TSH). * Targeted nodule accessible and eligible to HIFU * Absence of abnormal vocal cord mobility at laryngoscopy. * Nodule diameter ≥ 10mm measured by ultrasound. * Nodule volume inferior to 10 cc * Composition of the targeted nodule(s) : no more than 30% cystic Exclusion Criteria: * Head and/or neck disease that prevents hyperextension of neck. * Known history of thyroid cancer or other neoplasias in the neck region. * History of neck irradiation. * Macrocalcification inducing a shadow in the thyroid significant enough to preclude the HIFU treatment * Posterior position of the nodule if the thickness of the nodule is \<15mm * Pregnant or lactating woman * Any contraindication to the assigned analgesia/anaesthesia.