The Effect Of Aspirin On Survival in in Patients Undergoing Chronic Hemodialysis

Shanghai Jiao Tong University School of Medicine410 enrolled

Overview

The aim of present study is to examine the effect of low-dose aspirin on the incidence of cardiovascular events and mortality in patients undergoing chronic hemodialysis.

This study prospectively evaluate the impacts of low dose aspirin on survival and cardio-cerebral vascular events in a large cohort of Chinese patients undergoing chronic hemodialysis. Between January 2008, consecutive patients with hemodialysis with aspirin were enrolled.We examine the association of aspirin with all-cause mortality in patients matched by propensity scores using the Kaplan-Meier method and Cox models in "intention-to-treat" analyses.The secondary endpoint was rate of cardio-cerebral events.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

410

Conditions

Hemodialysis

Interventions

acetylsalicylic acidDRUG

75-100mg,per day

Eligibility

Sex: ALLMin age: 18 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: All patients aged 18 to 85, undergoing chronic hemodialysis, who have none of the following exclusion criteria. Exclusion Criteria: History of gastric or duodenal ulcers Known allergy to aspirin or other NSAIDs \-

Outcomes

Primary Outcomes

survival rate

Time frame: 5 years

Secondary Outcomes

cardio-cerebral event

Time frame: 5 years

Data from ClinicalTrials.gov

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