CBT Versus Selective Serotonin Reuptake Inhibitor For Treatment Of Depression In Temporal Lobe Epilepsy Patients

Inclusion Criteria: * With Major depressive disorder according to criteria from the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) * Diagnosed with TLE according to the criteria of the International League Against Epilepsy * Literates had sign an informed consent * Patients on antidepressant treatments will be allowed to participate only if they had been at stable doses for more than 8 weeks and still show signs of significant depression Exclusion Criteria: * Patients with high risk of suicide who required hospitalization * Patients who abused or are dependent on drugs * Those with a history of head trauma six months prior to the interview * Patients who have any condition that would prevent them from understanding the study or the psychotherapeutic process, such as mental retardation, psychosis, delirium, dementia, etc * Patients who have previously received CBT * Patients who have started, an antidepressant drug the last 8 weeks