Interest of Positive Expiratory Pressure (PEP) Delivery by EzPAP® After Cardiac Surgery in the Management of Postoperative Atelectasis

Nantes University Hospital80 enrolled

Overview

Pulmonary atelectasis is a frequent respiratory postoperative complication in cardiac surgery. Classically, the treatment of these patients is based on manual chest physiotherapy. Our objective is to evaluate the interest of association of positive end expiratory delivery sessions with the EzPAP® device. We perform a prospective monocentric, open label trial. Patients with atelectasis after scheduled cardiac surgery with cardiopulmonary bypass are included. They benefit from manual chest therapy and are randomised to receive or not positive end expiratory pressure sessions twice a day. The primary endpoint is the effect of this treatment on atelectasis radiological score after 2 days of treatment. The secondary endpoints are: oxygen saturation(SpO2)/inspired oxygen(FiO2) ratio, qualitative evaluation of ventilatory function, respiratory \& cardiac rate, pain, inspiratory pressure (sniff test), patient satisfaction, duration of intensive care unit (ICU) and hospital stay.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

SINGLE

Enrollment

Conditions

Pulmonary Atelectasis

Interventions

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients admitted in ICU after cardiac surgery by sternotomy with cardiopulmonary bypass presenting a pulmonary atelectasis after extubation, diagnosed by chest X-ray in postoperative period (day1 to day 2). * Patients over 18 years of age * Informed patient Exclusion Criteria: * Cardiac arrhythmia * Hemodynamic instability (mean blood pressure \< 65 mmHg or \> 95 mmHg) * Respiratory rate \> 35/min * Undrained pneumothorax * Predictable trachea intubation or emergent surgery * Patient oral refusal

Outcomes

Primary Outcomes

Radiological atelectasis score

This score was first described by Pasquina P et al in 2004

Time frame: Day 2 post-inclusion

Secondary Outcomes

Radiological atelectasis score

This score was first described by Pasquina P et al in 2004

Time frame: Days 1 and 3 post-inclusion

SpO2/FiO2 ratio

This ratio is measured before and after session