Inspiratory Muscle and Peripheral Muscle Training in Chronic Heart Failure

Naomi Kondo Nakagawa30 enrolled

Overview

Heart failure is a clinical syndrome that is the common end of several cardiac diseases with symptoms such as muscle fatigue, dyspnea and reduction of quality of life. To improve respiratory and general functional capacity of these patients, there are strategies that can be used such as inspiratory muscle training and peripheral muscle training (dynamic resistance training).

After agreement with the written informed consent, 35 subjects with severe heart failure were included in this study. They were randomized in three groups: controls, low-intensity and moderate-intensity group. All volunteers were assessed at Baseline and 8-weeks intervention. Cardiac events were registered following two years from baseline. The present study aimed to assess the effects of a combined program of inspiratory and peripheral muscle training on respiratory and general functional capacity and quality of life in patients with chronic heart failure.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Chronic Heart Failure

Interventions

controlOTHER

No intervention during the 8-weeks period of the study because of awaiting evaluation for cardiac rehabilitation or transplantation

moderate-intensity groupOTHER

Patients will be submitted to a 8-weeks training program with inspiratory muscle trained at 30% of the maximal inspiratory pressure (30 minutes/session/7 days/week) + peripheral muscle trained with exercises of upper limbs and lower limbs (50% 1 RM, increased every 2-weeks).

low-intensity groupOTHER

Patients will be submited to a 8 weeks training program, with inspiratory muscle trained at 15% of the maximal inspiratory pressure (30 minutes/session/7 days/week) + peripheral muscle trained with exercises of upper limbs and lower limbs (0,5 kg each)

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * chronic heart failure (functional class from NYHA II and III), * left ventricle ejection fraction bellow or equal 40%. Exclusion Criteria: * uncontrolled arrhythmia * pulmonary edema or pulmonary congestion in the last 30 days * peripheral oxygen saturation bellow 92% in resting condition * respiratory infection in the previous 30 days to the enrollment into the study * cognitive, neurological or orthopedic limitations

Locations (1)

Instituto Dante Pazzanese de Cardiologia

São Paulo, São Paulo, Brazil

Outcomes

Primary Outcomes

Change in respiratory muscle strength (in centimeters of water)

Inspiratory and expiratory muscle strength was assessed by using a pressure transducer (MVD-300 Microhard System, GlobalMed, Porto Alegre, Brazil).

Time frame: Before and after 8-weeks

Secondary Outcomes

walking distance

To assess functional capacity using walking distance (6-min walk test accordingly to ATS and ERS guidelines)

Time frame: Before and after 8-weeks

Data from ClinicalTrials.gov

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