The objective of the present study is to investigate the relative bioavailability of two BIIL 284 BS tablets (tablet C and tablet C) in comparison to the WIF tablet at a dose of 75 mg following a standard breakfast in healthy male volunteers
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
12
AUC0-∞ (Area under the concentration-time curve of the analyte in plasma over the time interval from 0 extrapolated to infinity)
Time frame: up to 72 hours after drug administration
Cmax (Maximum measured concentration of the analyte in plasma)
Time frame: up to 72 hours after drug administration
tmax (Time from dosing to the maximum concentration of the analyte in plasma)
Time frame: up to 72 hours after drug administration
t½ (Terminal half-life of the analyte in plasma)
Time frame: up to 72 hours after drug administration
MRTtot (Total mean residence time)
Time frame: up to 72 hours after drug administration
Vz/F (Apparent volume of distribution of the analyte during the terminal phase)
Time frame: up to 72 hours after drug administration
CLtot/F (Total clearance after oral administration)
Time frame: up to 72 hours after drug administration
Number of subjects with adverse events
Time frame: up to 8 days after last drug administration
Number of subjects with clinically findings in vital functions
blood pressure, pulse rate, ECG
Time frame: up to 8 days after last drug administration
Number of subjects with clinically findings in laboratory tests
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Time frame: up to 8 days after last drug administration