Comparison of Antimicrobial Coated Ureteral Stents With Non-coated Stents

Mansoura University110 enrolled

Overview

This study will be conducted to compare the efficacy of antimicrobial coated ureteral stent with non-coated stents in prevention of UTI in patients with ureteral stents

The efficacy of antimicrobial coated of ureteral stent with silver sulphadiazine in prevention of UTI in patients with ureteral stents will be studied by comparining the results of urine and stent cultures with patients who had non-coated ureteral stents. The impact of antimicrobeal stent coating on patients' quality of life will be evaluated with comparing the scores of ureteral stent symptom questionnaire between both groups.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

110

Conditions

Quality of Life

Interventions

Antimicrobeal coated stentsDEVICE

Patients in the intervention arm will undergo placement of (Silver Sulphdiazine) antimicrobeal coated stents

Eligibility

Sex: ALLMin age: 18 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients who will undergo ureteral stent placement Exclusion Criteria: * Patients allergic to sulpha containing medications * Ureteral stent insertion for infected hydronephrosis * Patients who developed septic complications requiring antibiotic treatment after stent placement * Patients who need bilateral stents * Patients with chronic kidney disease grade IV and V (GFR \<30ml/min) * Immunocompromised patients as those with malignancy or organ transplantation.

Locations (1)

Urology and Nephrology Center

Al Mansurah, Egypt

Outcomes

Primary Outcomes

Incidence of urinary tract infection (UTI)

UTI will be diagnosed with urine and stent culture of stent removal

Time frame: up to 3 months

Secondary Outcomes

Quality of life

The impact of stent coating on quality of life will be assissed with ureteral stent symptom questionnaire (USSQ)

Time frame: up to 3 months

Data from ClinicalTrials.gov

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