The primary outcome of the study is to evaluate the cumulative area under the concentration time curve (AUC) over 2 weeks, as measured by AUC from time 0 to 336 hours post dose (AUC0-336h), for serum concentrations of BIIB017 and Rebif. The secondary outcomes are to evaluate the maximum observed serum concentrations (Cmax) of BIIB017 and Rebif and to evaluate the safety and tolerability of BIIB017 and Rebif over 2 weeks in healthy volunteers.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
30
Administered as subcutaneous injection
Administered as subcutaneous injection
Research Site
Evansville, Indiana, United States
Cumulative area under the concentration-time curve (AUC), as measured by area under the concentration-time curve from time zero to 336 hours post dose (AUC0-336h)
Time frame: 2 weeks
Maximum observed serum concentration (Cmax) of BIIB017 and Rebif
Time frame: 2 weeks
Number of participants experiencing Adverse Events (AE) and Serious Adverse Events (SAE)
Time frame: Up to 4 weeks following treatment period
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