This is an open-label, multicenter, single-arm, expanded access study designed to provide alectinib to participants with ALK-rearranged NSCLC after disease progression on or intolerance to prior ALK tyrosine kinase inhibitor (TKI) therapy. Participants will receive alectinib until disease progression, unacceptable toxicity, withdrawal of consent, patient or physician decision to discontinue treatment, death, alectinib becomes commercially available in the United States following approval of alectinib by the FDA, or the Sponsor decides to close the trial, whichever occurs first (approximately 15 months).
Study Type
EXPANDED_ACCESS
Alectinib 600 mg administered orally with food.
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University of Alabama
Bimingham, Alabama, United States
Southern Cancer Center
Daphne, Alabama, United States
Southern Cancer Center
Mobile, Alabama, United States
Southern Cancer Center - Mobile
Mobile, Alabama, United States
Southern Cancer Center, PC
Mobile, Alabama, United States
Lalita Pandit Inc.
Fountain Valley, California, United States
University of California San Diego Medical Center; Moores Cancer Center
La Jolla, California, United States
Loma Linda Cancer Center
Loma Linda, California, United States
LAC USC Medical Center
Los Angeles, California, United States
University of Southern California
Los Angeles, California, United States
...and 35 more locations